Biomimetic synthesis of sclerin

TH Chan, P Brownbridge

Index: Chan, Tak-Hang; Brownbridge, Peter Journal of the Chemical Society, Chemical Communications, 1981 , # 1 p. 20 - 21

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Citation Number: 2

Abstract

A general synthesis of 3-hydroxy-homophthalates is developed and applied to the synthesis of sclerin (1), a developed and applied to the synthesis of sclerin (1), a compound possessing plant-growth activity; the critical step in the synthesis of (1) can be considered as the controlled condensation of a dicarbonyl unit with a tricarbonyl unit, in analogy to the biogensis of polyketides.