Unambiguous Synthesis of N-hydroxypeptides
T Kolasa, A Chimiak
Index: Kolasa,T.; Chimiak,A. Tetrahedron, 1977 , vol. 33, p. 3285 - 3288
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Citation Number: 22
Abstract
The large number of pcptide analogues so far obtained not only include depsipeptides' and hydrazino-peptides.' but also sulphamide' and phosphonic analogucs.' Since all these compounds differ drastically from their pro- totype. their physiological properties are radically changed. It is. however, very likely that the action of N-hydroxypcptides. which are closest to natural amides, will be only slightly modified. The possibility of peptide bond oxidation has not yet ...
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