Dynamic Kinetic Resolution of α??Amino Acid Esters in the Presence of Aldehydes
…, W Holla, T Riermeier, U Kragl, M Beller
Index: Schichl, Daniel A.; Enthaler, Stephan; Holla, Wolfgang; Riermeier, Thomas; Kragl, Udo; Beller, Matthias European Journal of Organic Chemistry, 2008 , # 20 p. 3506 - 3512
Full Text: HTML
Citation Number: 15
Abstract
Abstract A convenient procedure for the racemization of α-amino acid esters in the presence of catalytic amounts of salicylaldehydes is described. The combination of this racemization protocol with lipase-catalyzed ester hydrolysis allows successful dynamic kinetic resolution of various α-amino acid esters. The corresponding α-amino acids are obtained in high yield and optical purity.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, ...
Related Articles:
Simple conversion of fully protected amino acids to zwitterions
[Hao, Junliang; Reinhard, Matt; Henry, Steven S.; Seest, Eric P.; Belvo, Matthew D.; Monn, James A. Tetrahedron Letters, 2012 , vol. 53, # 12 p. 1433 - 1434]
[Asano, Yasuhisa; Nakazawa, Akiko Agricultural and Biological Chemistry, 1987 , vol. 51, # 7 p. 2035 - 2036]
[Riley, Dennis P.; Shumate, Robert E. Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5187 - 5193]
A mild Boc deprotection and the importance of a free carboxylate
[Thaqi, Ali; McCluskey, Adam; Scott, Janet L. Tetrahedron Letters, 2008 , vol. 49, # 49 p. 6962 - 6964]
Turtschamide, a cytotoxic putrescine bisamide from Corydalis turtschaninovii
[Tetrahedron Letters, , vol. 53, # 12 p. 1490 - 1492]