Suzuki cross-coupling of arylboronic acids mediated by a hydrosoluble Pd (0)/TPPTS catalyst

…, K Adiey, L Charruault, V Michelet, M Savignac…

Index: Dupuis, Christophe; Adiey, Kouacou; Charruault, Lise; Michelet, Veronique; Savignac, Monique; Genet, Jean-Pierre Tetrahedron Letters, 2001 , vol. 42, # 37 p. 6523 - 6526

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Citation Number: 132

Abstract

Suzuki cross-coupling reactions between a range of aryl bromides and boronic acids using a water-soluble Pd (0)/TPPTS catalyst occur under mild conditions with high efficiency. The process tolerates electron-rich and electron-poor substituents and provides an efficient access to sterically hindered biaryls. Good turnovers are observed and the catalyst can be recycled three times without loss of activity.

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