Diastereospecific Enolate Addition and Atom-Efficient Benzimidazole Synthesis for the Production of L/T Calcium Channel Blocker ACT-280778

…, R Litjens, T Seidel, M Struijk…

Index: Cardwell, Terence J.; Edwards, Alison J.; Hartshorn, Richard M.; Holmes, Rodney J.; McFadyen, W. David Australian Journal of Chemistry, 1997 , vol. 50, # 10 p. 1009 - 1015

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Citation Number: 3

Abstract

... Search text Anywhere Org. Process Res. Dev. All Publications/Website. Select a Journal or Book ... In campaign 2, seven batches of 4·2 HCl (141 kg) were produced from the HCl salt 12a·2 HCl with high assay (72% w/w) and purity (100% a/a HPLC). ...