Synthesis of ring-substituted phenyl hydrazinecarboxylates and study of their protonation in dimethyl sulfoxide solutions

P Vlasák, P Pařík, J Klicnar, J Mindl

Index: Vlasak, Petr; Parik, Patrik; Klicnar, Jiri; Mindl, Jaromir Collection of Czechoslovak Chemical Communications, 1998 , vol. 63, # 6 p. 793 - 802

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Citation Number: 5

Abstract

Abstract The pK a values of nineteen phenyl hydrazinecarboxylate hydrochlorides RC 6 H 4 OCONHNH 2· HCl (R= H, 3-and 4-Cl, 3-and 4-O 2 N, 4-Me) and their 1-methyl or 2-methyl derivatives were determined by potentiometric titration with tetrabutylammonium hydroxide in DMSO. IR spectra of the hydrazinecarboxylates and their hydrochlorides revealed that the hydrazinecarboxylate protonation occurs at N 2. The methods of synthesis of phenyl ...