Tetrahedron

Development of a palladium-catalyzed decarboxylative cross-coupling of (2-azaaryl) carboxylates with aryl halides

CK Haley, CD Gilmore, BM Stoltz

Index: Haley, Christopher K.; Gilmore, Christopher D.; Stoltz, Brian M. Tetrahedron, 2013 , vol. 69, # 27-28 p. 5732 - 5736

Full Text: HTML

Citation Number: 23

Abstract

A catalytic method for the decarboxylative coupling of 2-(azaaryl) carboxylates with aryl halides is described. The decarboxylative cross-coupling presented is mediated by a system catalytic in both palladium and copper without requiring stoichiometric amounts of organometallic reagents or organoboronic acids. This method circumvents additional synthetic steps required to prepare 2-azaaryl organometallics and organoborates as ...

Related Articles:

Microwave-assisted Negishi and Kumada cross-coupling reactions of aryl chlorides

[Walla, Peter; Kappe, C. Oliver Chemical Communications, 2004 , # 5 p. 564 - 565]

The preparation of a stable 2-pyridylboronate and its reactivity in the Suzuki–Miyaura cross-coupling reaction

[Hodgson, Paul B.; Salingue, Fabrice H. Tetrahedron Letters, 2004 , vol. 45, # 4 p. 685 - 687]

Palladium-catalysed cross-coupling of 2-trimethylsilylpyridine with aryl halides

[Napier, Spencer; Marcuccio, Sebastian M.; Tye, Heather; Whittaker, Mark Tetrahedron Letters, 2008 , vol. 49, # 44 p. 6314 - 6315]

The preparation of a stable 2-pyridylboronate and its reactivity in the Suzuki–Miyaura cross-coupling reaction

[Hodgson, Paul B.; Salingue, Fabrice H. Tetrahedron Letters, 2004 , vol. 45, # 4 p. 685 - 687]

Palladium-catalysed cross-coupling of 2-trimethylsilylpyridine with aryl halides

[Napier, Spencer; Marcuccio, Sebastian M.; Tye, Heather; Whittaker, Mark Tetrahedron Letters, 2008 , vol. 49, # 44 p. 6314 - 6315]

More Articles...