Palladium-catalyzed coupling of thiol esters with aryl and primary and secondary alkyl organoindium reagents

BW Fausett, LS Liebeskind

Index: Fausett, Bryan W.; Liebeskind, Lanny S. Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4851 - 4853

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Citation Number: 72

Abstract

Thiol esters and organoindium reagents undergo palladium-catalyzed cross-coupling under mild conditions to give ketones in moderate to excellent yields. Aryl and primary/secondary alkyl organoindium reagents can be used as coupling partners. This method has two advantages over the cross-coupling of thiol esters with boron and tin reagents:(1) no added copper reagent is required to mediate the reaction and (2) for the case of alkyl transfer, no ...