Tetrahedron Letters

Ligand free open air copper (II) mediated aryl formamidation and amination of aryl halides

R Komati, BS Jursic

Index: Komati, Rajesh; Jursic, Branko S. Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1523 - 1527

Full Text: HTML

Citation Number: 1

Abstract

Abstract A simple synthetic procedure for direct formamidation and amination of aryl halides mediated by copper (II) salts was developed in open air, without an external ligand in formamide with potassium carbonate as a base. This approach is particularly efficient when electron active aryl halides are used as substrates. In these cases almost quantitative formamidation was observed.

Related Articles:

Nano-MgO: an efficient catalyst for the synthesis of formamides from amines and formic acid under MWI

[Reddy, M. B. Madhusudana; Ashoka; Chandrappa; Pasha Catalysis Letters, 2010 , vol. 138, # 1-2 p. 82 - 87]

Deep eutectic solvent promoted highly efficient synthesis of N, N'-diarylamidines and formamides

[Azizi, Najmadin; Gholibeglo, Elham; Babapour, Mahbobe; Ghafuri, Hossein; Bolourtchian, Seyed Mohammad Comptes Rendus Chimie, 2012 , vol. 15, # 9 p. 768 - 773]

Iron and ruthenium carbonyl catalyzed reductive carbonylation of nitro compounds by sodium methoxide. A significant effect of the metal on the reaction course

[Journal of the American Chemical Society, , vol. 103, # 21 p. 6514 - 6515]

Mn-promoted aerobic oxidative C–C bond cleavage of aldehydes with dioxygen activation: A simple synthetic approach to formamides

[Zhang, Chun; Xu, Zejun; Shen, Tao; Wu, Guolin; Zhang, Liangren; Jiao, Ning Organic Letters, 2012 , vol. 14, # 9 p. 2362 - 2365]

A Very Simple, Highly Efficient and Catalyst-free Procedure for the NFormylation of Amines Using Triethyl orthoformate in Water Under Ultrasound-irradiation

[Habibi, Davood; Sahebekhtiari, Hesam; Nasrollahzadeh, Mahmoud; Taghipour, Ahmad Letters in Organic Chemistry, 2013 , vol. 10, # 3 p. 209 - 212]

More Articles...