Tetrahedron

Synthesis of substituted α, β-unsaturated δ-lactones from vinyl tellurides

JM Oliveira, JCR Freitas, JV Comasseto, PH Menezes

Index: Oliveira, Juliana M.; R. Freitas, Juliano C.; Comasseto, Joao Valdir; Menezes, Paulo Henrique Tetrahedron, 2011 , vol. 67, # 16 p. 3003 - 3009

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Citation Number: 23

Abstract

A new approach for the synthesis of α, β-unsaturated δ-lactones, a unit present in many natural products with interesting biological activities is described. The approach was based on the use of a vinyl telluride, and it is complementary to the methods using ring-closing metathesis. The sequence was performed in good overall yield with retention of the Z- double bond geometry.

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