Practical catalyst for cyclic metathesis. Synthesis of functional and/or enantiopure cycloalkenes.

…, J Feldman, JC Calabrese

Index: Nugent, William A.; Feldman, Jerald; Calabrese, Joseph C. Journal of the American Chemical Society, 1995 , vol. 117, # 35 p. 8992 - 8998

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Citation Number: 106

Abstract

Abstract: The oxo-tungsten complex trans-WOCl2 (OAr) 2 (AI= 2, 6-dibromophenyl) is prepared by reaction of WOCb with 2 equiv of 2, 6-dibromophenol. A variety of nonconjugated dienes are cleanly cyclized to the corresponding cycloalkenes using 2 mol% of this catalyst in combination with 4 mol% of tetraethyllead. All three components of the catalyst system are commercially available. The catalytic reactions are typically complete ...

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