BACTERIOSTATS: V. THE PREPARATION AND BACTERIOSTATIC PROPERTIES OF AMIDINE DERIVATIVES

DL Garmaise, RW Kay, R Gaudry…

Index: Garmaise,D.L. et al. Canadian Journal of Chemistry, 1961 , vol. 39, p. 1493 - 1501

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Citation Number: 4

Abstract

Coinpounds with uilsubstituted arnidine groups have been employed as chemothera- peutic agents (1) but there have been relatively few investigations of N-substituted amidines. Some bacteriostatically active N-substituted rnonoainidines were found (2) to be too toxic for use in guinea pig infections. A series of N,N1-bis-(a1l;yl)-adipamidines and -sebacamidiiles has been patented (3) for use in disinfectant compositions, and high bacteriostatic activity has been ...