α-EWG-substituted enones: Suitable substrates for ring-closing metathesis

J Toueg, J Prunet

Index: Toueg, Julie; Prunet, Joelle Synlett, 2006 , # 17 p. 2807 - 2811

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Citation Number: 10

Abstract

We first focused on the synthesis of 5-membered ring enone 5. Surprisingly, very few methods exist for the synthesis of cyclic α-carbalkoxyenones that do not require the use of selenium derivatives, even though such motives have proved to be valuable synthetic intermediates for total synthesis. [8] Noteworthy though is the work of Ikeda [9] that uses a rhodium-catalysed CH insertion followed by spontaneous elimination on silica gel, intramolecular Knoevenagel ...