Titanium-mediated cyclizations of. beta.-keto esters with acetals: a convenient route to 2-carbalkoxycycloalkenones
RL Funk, JF Fitzgerald, TA Olmstead…
Index: Funk, Raymond L.; Fitzgerald, John F.; Olmstead, Thomas A.; Para, Kim S.; Wos, John A. Journal of the American Chemical Society, 1993 , vol. 115, # 19 p. 8849 - 8850
Full Text: HTML
Citation Number: 27
Abstract
The preparation of both carbocycles and heterocycles by Lewis acid-mediated cyclization reactions of acetals' has become a welldocumented synthetic strategy following the pioneering investigations of Johnson, who showed that acetals with appropriately positioned olefinic bonds undergo facile closure to mono-or polycyclic products. 2 More recently, extension of the Mukaiyama cross-aldol reaction (TiCl4-promoted condensation of ...
Related Articles:
[Wang, Cunxiao; Gu, Xin; Yu, Marvin S.; Curran, Dennis P. Tetrahedron, 1998 , vol. 54, # 29 p. 8355 - 8370]
[Wang, Cunxiao; Gu, Xin; Yu, Marvin S.; Curran, Dennis P. Tetrahedron, 1998 , vol. 54, # 29 p. 8355 - 8370]
[Duschek, Alexander; Kirsch, Stefan F. Chemistry - A European Journal, 2009 , vol. 15, # 41 p. 10713 - 10717]
Facile and efficient preparation of alkyl 6-oxo-1-cyclohexenecarboxylates
[Kato, Michiharu; Kamat, Vijayendra P.; Yoshikoshi, Akira Synthesis, 1988 , # 9 p. 699 - 701]
α-EWG-substituted enones: Suitable substrates for ring-closing metathesis
[Toueg, Julie; Prunet, Joelle Synlett, 2006 , # 17 p. 2807 - 2811]