Formation of reissert analogs from benzimidazole and use of carboxylic acids in a retro??reissert reactionReissert Analogs from Benzimidazole

…, YP Ho, DLW Burford, FD Popp

Index: Uff, Barrie C.; Ho, Yee-Ping; Burford, Donald L. W.; Popp, Frank D. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1349 - 1351

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Citation Number: 15

Abstract

Abstract Reissert analogs have been formed in high yields from benzimidazole using trimethylsilyl cyanide and chloroformates. A retro-Reissert reaction can be effected on the products, their carbon-2 alkylated derivatives and benzothiazole analogs, by treatment with hexanoic or benzoic acids.

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