Formation of optically active 3-hydroxypiperidines
J Cossy, C Dumas, P Michel, DG Pardo
Index: Cossy, Janine; Dumas, Cecile; Michel, Patrick; Pardo, Domingo Gomez Tetrahedron Letters, 1995 , vol. 36, # 4 p. 549 - 552
Full Text: HTML
Citation Number: 57
Abstract
2: oil: MS (EI, 70eV) m/e 191 (M + , 34), 100 (45) 91 (100): IR (film, cm −1 ) 3360; 1 H NMR (300MHz, CDCl 3 ) δ 1.44–1.75 (m, 4H) 2.19–2.44 (m, 4H) 2.80–3.00 (s broad, 1H) 3.43 (s, 2H) 3.69–3.75 (m, 1H), 7.18–7.24 (m, 5H); 13 C NMR (75MHz, CDCl 3 ) 21.6 (t) 31.6 (t) 53.3 (t) 60.1 (t) 62.9 (t) 66.1 (d) 127.0 (d) 128.1 (d. 2C) 129.0 (d. 2C) 137.8 (s). ... The enantiomeric excess was determined by NMR. ... Compound 5 is obtained by the reduction of ...
Related Articles:
Synthesis and Reaction of 1-Azabicyclo [3.1. 0] hexane
[Hayashi, Kazuhiko; Kujime, Eiko; Katayama, Hajime; Sano, Shigeki; Shiro, Motoo; Nagao, Yoshimitsu Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 10 p. 1142 - 1146]
[Li, Run-Lin; Liu, Gong-Qing; Li, Wei; Wang, Yu-Mei; Li, Lin; Duan, Lili; Li, Yue-Ming Tetrahedron, 2013 , vol. 69, # 29 p. 5867 - 5873]