One-pot preparation of 3-chloropiperidine compounds via Cu (II)-promoted intramolecular chloroamination of unfunctionalized olefins
RL Li, GQ Liu, W Li, YM Wang, L Li, L Duan, YM Li
Index: Li, Run-Lin; Liu, Gong-Qing; Li, Wei; Wang, Yu-Mei; Li, Lin; Duan, Lili; Li, Yue-Ming Tetrahedron, 2013 , vol. 69, # 29 p. 5867 - 5873
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Citation Number: 11
Abstract
3-Chloropiperidine compounds were obtained via Cu (II)-promoted one-pot intramolecular chloroamination of N-benzyl-4-penten-1-amines and subsequent rearrangement. The reaction conditions leading to this skeleton were studied, and the structure of the product was confirmed by NMR as well as X-ray diffraction experiments.
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