Canadian Journal of Chemistry
Pyrones. IX. Synthetic approaches to the fungal metabolite phacidin and its derivatives
GA Poulton, TD Cyr
Index: Poulton; Cyr Canadian Journal of Chemistry, 1982 , vol. 60, # 22 p. 2821 - 2829
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Citation Number: 18
Abstract
The synthesis of the antibiotic fungal metabolite phacidin 1 (4-methoxy-6-nonanoyl-2 H- pyran-2-one-3-carboxaldehyde) and two related compounds is reported. Phacidin has been prepared in four steps from the readily available triacetic acid lactone (4-hydroxy-6-methyl-2
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