Tetrahedron

Competition between vinylic substitution and conjugate addition in the reactions of vinyl selenoxides and vinyl selenones with nucleophiles in DMF

M Tiecco, D Chianelli, L Testaferri, M Tingoli, D Bartoli

Index: Tiecco, Marcello; Chianelli, Donatella; Testaferri, Lorenzo; Tingoli, Marco; Bartoli, Donatella Tetrahedron, 1986 , vol. 42, # 17 p. 4889 - 4896

Full Text: HTML

Citation Number: 29

Abstract

Vinyl selenoxides and vinyl selenones present a different reactivity towards thiolate or alkoxide anions in DMF. In the case of selenoxides the addition of the nucleophiles regioselectively occurs at the α-carbon leading to the formation of the vinylic substitution products with complete retention of configuration. These reactions occur under very mild conditions indicating that the seleninyl group markedly enhances nucleophilic vinylic ...

Related Articles:

Diazo compounds and phenyliodonium ylides in inter-and intramolecular cyclopropanations catalyzed by dirhodium (II). Synthesis and chiral resolution by GC versus …

[Ghanem, Ashraf; Lacrampe, Fabienne; Aboul-Enein, Hassan Y.; Schurig, Volker Monatshefte fur Chemie, 2005 , vol. 136, # 7 p. 1205 - 1219]

Formal Homo??Nazarov and Other Cyclization Reactions of Activated Cyclopropanes

[De Simone, Filippo; Saget, Tanguy; Benfatti, Fides; Almeida, Sofia; Waser, Jerome Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14527 - 14538]

S-Ethenylsulfoximine derivatives. Reagents for ethylenation of protic nucleophiles

[Johnson, Carl R.; Lockard, James P.; Kennedy, Eugene R. Journal of Organic Chemistry, 1980 , vol. 45, # 2 p. 264 - 271]

S-Ethenylsulfoximine derivatives. Reagents for ethylenation of protic nucleophiles

[Johnson, Carl R.; Lockard, James P.; Kennedy, Eugene R. Journal of Organic Chemistry, 1980 , vol. 45, # 2 p. 264 - 271]

S-Ethenylsulfoximine derivatives. Reagents for ethylenation of protic nucleophiles

[Johnson, Carl R.; Lockard, James P.; Kennedy, Eugene R. Journal of Organic Chemistry, 1980 , vol. 45, # 2 p. 264 - 271]

More Articles...