Formal Homo??Nazarov and Other Cyclization Reactions of Activated Cyclopropanes

…, T Saget, F Benfatti, S Almeida, J Waser

Index: De Simone, Filippo; Saget, Tanguy; Benfatti, Fides; Almeida, Sofia; Waser, Jerome Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14527 - 14538

Full Text: HTML

Citation Number: 47

Abstract

Abstract The Nazarov cyclization of divinyl ketones gives access to cyclopentenones. Replacing one of the vinyl groups by a cyclopropane leads to a formal homo-Nazarov process for the synthesis of cyclohexenones. In contrast to the Nazarov reaction, the cyclization of vinyl-cyclopropyl ketones is a stepwise process, often requiring harsh conditions. Herein, we describe two different approaches for further polarization of the ...

Related Articles:

Reductive cleavage of N O bonds in hydroxylamine and hydroxamic acid derivatives using SmI 2/THF

[Keck, Gary E.; McHardy, Stanton F.; Wager, Travis T. Tetrahedron Letters, 1995 , vol. 36, # 41 p. 7419 - 7422]

A facile deprotection of secondary acetamides

[Koenig, Stefan G.; Vandenbossche, Charles P.; Zhao, Hang; Mousaw, Patrick; Singh, Surendra P.; Bakale, Roger P. Organic Letters, 2009 , vol. 11, # 2 p. 433 - 436]

Reductive N-alkylation of amides, carbamates and ureas

[Dube, Daniel; Scholte, Andrew A. Tetrahedron Letters, 1999 , vol. 40, # 12 p. 2295 - 2298]

Synthetic and structural studies on 1, 2, 4-dithiazolidine-3, 5-dione derivatives

[Wood, Mark E.; Cane-Honeysett, Daniel J.; Dowle, Michael D.; Coles, Simon J.; Hursthouse, Michael B. Organic and Biomolecular Chemistry, 2003 , vol. 1, # 17 p. 3015 - 3023]

Alkyl 1-chloroalkyl carbonates: Reagents for the synthesis of carbamates and protection of amino groups

[Barcelo, Gerard; Senet, Jean-Pierre; Sennyey, Gerard; Bensoam, Jean; Loffet, Albert Synthesis, 1986 , # 8 p. 627 - 632]

More Articles...