Tetrahedron Letters

Regioselective iridium (I)-catalysed remote borylation of oxygenated naphthalenes

P Hume, DP Furkert, MA Brimble

Index: Hume, Paul; Furkert, Daniel P.; Brimble, Margaret A. Tetrahedron Letters, 2012 , vol. 53, # 29 p. 3771 - 3773

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Citation Number: 4

Abstract

We present our investigations into the regioselective borylation and halogenation of polyoxygenated naphthalene systems that are key precursors to dimeric pyranonaphthoquinone natural products. A variety of oxygenated naphthalenes were successfully borylated with pinacolborane in high yield and excellent regioselectivity using [Ir (COD) OMe] 2 and di-tert-butylbipyridine (dtbpy). The boronates were also readily ...

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