Agonists for the adenosine A1 receptor with tunable residence time. A case for nonribose 4-amino-6-aryl-5-cyano-2-thiopyrimidines

J Louvel, D Guo, M Agliardi, TAM Mocking…

Index: Daboun, Hamed A.; El-Reedy, Ahmed M. Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1983 , vol. 38, # 12 p. 1686 - 1689

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Citation Number: 18

Abstract

... Volume: Page: Digital Object Identifier (DOI). ... R 1, K i (nM) ± SEM or disp. at 1 μM (%) a, KRI b, k on (M –1 min –1 ) d, k off (min –1 ) e (RT (min)) f. 24, 4-O(CH 2 ) 2 OH, 4.8 ± 0.1, 1.18 ± 0.09, 25, 4-NHAc, 14 ± 0.5, 0.97 ± 0.09, ...