A new, simple procedure for the synthesis of formyl amides
L De Luca, G Giacomelli, A Porcheddu, M Salaris
Index: De Luca, Lidia; Giacomelli, Giampaolo; Porcheddu, Andrea; Salaris, Margherita Synlett, 2004 , # 14 p. 2570 - 2572
Full Text: HTML
Citation Number: 38
Abstract
Abstract A simple and mild method for the N-formylation of amines and α-amino esters is described via reaction with 2-chloro-4, 6-dimethoxy [1, 3, 5] triazine and formic acid. The reaction can be accelerated under microwave irradiation and yields the N-formyl species in high yields and without racemization in the case of optically active α-amino esters.
Related Articles:
[Yang, Dongsik; Jeon, Heung Bae Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 5 p. 1424 - 1426]
Preparation of Protein Conjugates via Homobifunctional Diselenoester Cross-Linker
[Lavastre, Isabelle; Besancon, Jack; Moiese, Claude; Brossier, Pierre Bulletin de la Societe Chimique de France, 1995 , vol. 132, # 2 p. 188 - 195]
Photochemistry of N-nitroso-N-alkyl amino acids: a facile oxidative decarboxylation
[Chow, Yuan L.; Horning, Douglas P.; Polo, Joel Canadian Journal of Chemistry, 1980 , vol. 58, p. 2477 - 2483]