A facile one-pot solid-phase synthesis of oxazolidin-2-ones using polymer-supported 2-hydroxyalkyl selenide reagent
QS Hu, SR Sheng, SY Lin, MH Wei…
Index: Hu, Qiao-Sheng; Sheng, Shou-Ri; Lin, Shu-Ying; Wei, Mei-Hong; Xin, Qin; Liu, Xiao-Ling Journal of Chemical Research, 2007 , # 2 p. 74 - 75
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Abstract
A simple, efficient and environmentally friendly procedure for one-pot solid-phase synthesis of 2-oxazolidinones in moderate to good yields by reaction of polystyrene-supported 2- hydroxyalkyl selenide with benzoyl isocyanate and subsequent oxidation/cyclisation- hydrolysis using a selenium traceless linker strategy is described.
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