Highly Regioselective Anti-Markovnikov Palladium-Borate-Catalyzed Methoxycarbonylation Reactions: Unprecedented Results for Aryl Olefins
TO Vieira, MJ Green, H Alper
Index: Vieira, Tiago O.; Green, Mike J.; Alper, Howard Organic Letters, 2006 , vol. 8, # 26 p. 6143 - 6145
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Citation Number: 37
Abstract
A general, highly efficient and regioselective methoxycarbonylation, by means of a palladium-salicylicborate-catalyzed protocol, of terminal alkyl and aryl olefins is described. The substrates include aliphatic alkenes, allylbenzenes, and styrene derivatives. The yields are very good (60-92%) and the regioselectivity, in favor of the linear ester, is up to quantitative unprecedented in the case of styrenes.
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