Monooxygenation of aromatic compounds by dioxygen with bioinspired systems using non-heme iron catalysts and tetrahydropterins: comparison with other reducing …

D Mathieu, JF Bartoli, P Battioni, D Mansuy

Index: Mathieu, Delphine; Bartoli, Jean Francois; Battioni, Pierrette; Mansuy, Daniel Tetrahedron, 2004 , vol. 60, # 17 p. 3855 - 3862

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Citation Number: 23

Abstract

Monooxygenation of aromatic compounds by dioxygen in the presence of catalytic amounts of an iron (II) salt and tetrahydropterins as reducing agents occurs with a regioselectivity favouring meta-hydroxylation of arenes bearing an electron-donating substituent, such as anisole, phenetole, toluene, and ethylbenzene. Comparison of similar systems using various reducing agents showed that only tetrahydropterins and ascorbate led to such a major ...