Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents: Part II: Alkylation far away from the amino function

C Glende, M Klein, H Schmitt, L Erdinger…

Index: Glende, Carsten; Klein, Markus; Schmitt, Heimo; Erdinger, Lothar; Boche, Gernot Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2002 , vol. 515, # 1-2 p. 15 - 38

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Citation Number: 23

Abstract

Alkyl and trifluoromethyl derivatives of 4-aminobiphenyl (1)(4ABP) and 2-aminofluorene (7)(2AF) were synthesised and assayed for mutagenicity using Salmonella typhimurium tester strains TA98 and TA100 with and without the addition of S9 mix. Modification of 1 ...

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