Boronic acid-based autoligation of nucleic acids: influence of the nature of the 3′-end ribonucleotidic strand

R Barbeyron, J Wengel, JJ Vasseur…

Index: Barbeyron, Renaud; Wengel, Jesper; Vasseur, Jean-Jacques; Smietana, Michael Monatshefte fur Chemie, 2013 , vol. 144, # 4 p. 495 - 500

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Citation Number: 4

Abstract

Abstract The development of synthetic systems displaying dynamic and adaptive characteristics is a formidable challenge with wide applications from biotechnology to therapeutics. Recently, we described a dynamic and programmable nucleic acid-based system relying on the formation of reversible boronate internucleosidic linkages. The DNA-or RNA-templated system comprises a 5′-ended boronic acid probe connecting a 3′- ...