Ptaquiloside, a potent carcinogen isolated from bracken fern pteridiumaquilinum var. latiusculum: structure elucidation based on chemical and spectral evidence, and …

M Ojika, K Wakamatsu, H Niwa, K Yamada

Index: Ojika, Makoto; Wakamatsu, Kazumasa; Niwa, Haruki; Yamada, Kiyoyuki Tetrahedron, 1987 , vol. 43, # 22 p. 5261 - 5274

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Citation Number: 82

Abstract

The structure of ptaquiloside (1), a potent carcinogenic compound isolated from bracken fern, Pteridium aquilinum var. latiusculum has been elucidated on the basis of chemical and spectral evidence. The dienone 3 generated from 1 under alkaline conditions was shown to be a strong alkylating agent. For the purpose of obtaining the preliminary information on chemical modification of biopolymers such as proteins and DNA with the dienone 3, ...