Synlett

Total synthesis of pterosines B and C via a photochemical key step

P Wessig, J Teubner

Index: Wessig, Pablo; Teubner, Janek Synlett, 2006 , # 10 p. 1543 - 1546

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Citation Number: 34

Abstract

Abstract A total synthesis of pterosines B and C is reported. Starting with a fourfold substituted benzene derivative, the introduction of the remaining substituents is mainly based on Sonogashira couplings followed by different transformations of the ethyne moiety. The key step is a photochemical ring-closure of an α-mesyloxy ketone forming the 1- indanone skeleton.