Catalyst-free synthesis of 3-hydroxy-3-(alkyl/aryl) indolin-2-ones by addition of organoaluminum reagents to isatins

…, P Ramesh, AS Kumar, A Swetha, HM Meshram

Index: Kumar, G. Santosh; Ramesh, Palakuri; Kumar, A. Sanjeeva; Swetha; Meshram Tetrahedron Letters, 2013 , vol. 54, # 37 p. 5048 - 5051

Full Text: HTML

Citation Number: 5

Abstract

Abstract An efficient synthesis of 3-hydroxy-3-(alkyl/aryl) indol-2-one derivatives has been described by the reactions of isatin with organoaluminum reagents. The reaction is very rapid and yields are high. The protocol is applicable for substituted isatins as well as a variety of organoaluminums.

Related Articles:

Diastereoselective synthesis of 3, 3-disubstituted oxindoles from atropisomeric N-aryl oxindole derivatives

[Nakazaki, Atsuo; Mori, Ayako; Kobayashi, Susumu; Nishikawa, Toshio Tetrahedron Letters, 2012 , vol. 53, # 52 p. 7131 - 7134]

CeCl 3· 7H 2 O/IBX-promoted oxidation of 3-alkylindoles to 3-hydroxyoxindoles

[Yadav; Reddy, B.V. Subba; Reddy, Ch. Suresh; Krishna Tetrahedron Letters, 2007 , vol. 48, # 11 p. 2029 - 2032]

A novel biotransformation of benzofurans and related compounds catalysed by a chloroperoxidase

[Alvarez, Ricardo G.; Hunter, Iain S.; Suckling, Colin J.; Thomas, Michael; Vitinius, Ute Tetrahedron, 2001 , vol. 57, # 40 p. 8581 - 8587]

More Articles...