DDQ-mediated direct cross-dehydrogenative-coupling (CDC) between benzyl ethers and simple ketones
Y Zhang, CJ Li
Index: Zhang, Yuhua; Li, Chao-Jun Journal of the American Chemical Society, 2006 , vol. 128, # 13 p. 4242 - 4243
Full Text: HTML
Citation Number: 252
Abstract
A direct Cross-Dehydrogenative-Coupling (CDC) between benzyl ethers and simple ketones was developed without using any metal catalyst. By using DDQ, various benzyl ethers and simples ketones were coupled together directly to form β-alkoxyl ketones efficiently. A mechanism in which the DDQ serves the double roles of an oxidizing agent and an organomediator was proposed.
Related Articles:
[Li, Lian-Sheng; Das, Sanjib; Sinha, Subhash C. Organic Letters, 2004 , vol. 6, # 1 p. 127 - 130]
[Iwasawa, Nobuharu; Mukaiyama, Teruaki Chemistry Letters, 1987 , p. 463 - 466]
Tris (pentafluorophenyl) boron as an Efficient, Air Stable, and Water Tolerant Lewis Acid Catalyst.
[Ishihara, Kazuaki; Hanaki, Naoyuki; Funahashi, Miyuki; Miyata, Mayumi; Yamamoto, Hisashi Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 6 p. 1721 - 1730]