An essentially mild and efficient catalyst system for the activation of carbonyl compounds and their derivatives. The combined use of trimethylsilyl chloride and tin (II) …

N Iwasawa, T Mukaiyama

Index: Iwasawa, Nobuharu; Mukaiyama, Teruaki Chemistry Letters, 1987 , p. 463 - 466

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Citation Number: 58

Abstract

An essentially mild and efficient catalyst system, the combined use of trimethylsilyl chloride and tin (II) chloride, is effectively employed for the activation of acetals, aldehydes, orthoesters, and α, β-unsaturated ketones to accomplish the reaction with silyl enol ethers to give the corresponding addition products in good yields.