Synthesis and antitumor activities of novel α-aminophosphonates dehydroabietic acid derivatives
XC Huang, M Wang, YM Pan, XY Tian, HS Wang…
Index: Huang, Xiao-Chao; Wang, Meng; Pan, Ying-Ming; Tian, Xiao-Yan; Wang, Heng-Shan; Zhang, Ye Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 19 p. 5283 - 5289
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Citation Number: 22
Abstract
Abstract A series of novel α-aminophosphonate derivatives containing DHA structure were designed and synthesized as antitumor agents. In vitro antitumor activities of these compounds against the NCI-H460 (human lung cancer cell), A549 (human lung adenocarcinoma cell), HepG2 (human liver cancer cell) and SKOV3 (human ovarian cancer cell) human cancer cell lines were evaluated and compared with commercial anticancer ...
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