Neuroleptics of the 8-methylthio-10-piperazino-10, 11-dihydrodibenzo [b, f] thiepin series: New compounds and new procedures
J Jílek, J Pomykáček, A Dlabač…
Index: Jilek; Pomykacek; Dlabac; et al. Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 2 p. 504 - 516
Full Text: HTML
Citation Number: 7
Abstract
Abstract Heating of 8-methylthiodibenzo [b, f] thiepin-10 (11H)-one with mono-p- toluenesulfonates of 1-methylpiperazine and piperazine in vacuo led in good yields to the enamines IX-XI, the first of which was reduced with zinc and acetic acid to the base I (methiothepin). The ester III (oxyprothepindecanoate) was obtained by reaction of the amino alcohol II (oxyprothepin) with decanoic acid in the presence of N, N'-carbonyldiimidazole ...
Related Articles:
[Curran, Dennis P.; Liu, Hui; Josien, Hubert; Ko, Sung-Bo Tetrahedron, 1996 , vol. 52, # 35 p. 11385 - 11404]
Organoiodinane oxyanions as reagents for the cleavage of a reactive phosphate
[Moss, Robert A.; Chatterjee, Swati; Wilk, Boguslawa Journal of Organic Chemistry, 1986 , vol. 51, # 22 p. 4303 - 4307]
A Practical, Automated Synthesis of meta-[18F] Fluorobenzylguanidine for Clinical Use
[Landge, Kamalkishor P.; Jang, Keun Sam; Lee, Sang Yeul; Chi, Dae Yoon Journal of Organic Chemistry, 2012 , vol. 77, # 13 p. 5705 - 5713]
[Larock, Richard C.; Tu, Chi; Pace, Paola Journal of Organic Chemistry, 1998 , vol. 63, # 20 p. 6859 - 6866]
A Practical, Automated Synthesis of meta-[18F] Fluorobenzylguanidine for Clinical Use
[Landge, Kamalkishor P.; Jang, Keun Sam; Lee, Sang Yeul; Chi, Dae Yoon Journal of Organic Chemistry, 2012 , vol. 77, # 13 p. 5705 - 5713]