Reaction of β-Alkoxyacrylic Esters with Secondary Amines

PL Benneville, JH Macartney

Index: De Benneville; Macartney Journal of the American Chemical Society, 1950 , vol. 72, p. 3725

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Citation Number: 7

Abstract

Replacement of an ether group with an amino group requires a particularly favorable structural condition in the molecule. Cook and Dixonl have succeeded in so replacing the ether group by heating p-alkoxypropionitriles with amines in an autoclave to temperatures generally in the neighborhood of 200'. This reaction can be attributed to the presence of the cyanide group in a neighboring position to the alkoxy group, with consequent weakening ...