Stereoselective Palladium??Catalyzed Carboaminoxylations of Indoles with Arylboronic Acids and TEMPO
S Kirchberg, R Fröhlich, A Studer
Index: Kirchberg, Sylvia; Froehlich, Roland; Studer, Armido Angewandte Chemie, International Edition, 2009 , vol. 48, # 23 p. 4235 - 4238
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Citation Number: 101
Abstract
Abstract Indoles are not indolent: Various indoles react with arylboronic acids chemodivergently. C [BOND] H arylation of free indole and N-methylindole gives the corresponding C (2)-arylated indoles A whereas N-acylated, N-benzoylated, and N-Boc- protected indoles provide the corresponding arylcarboaminoxylated products B with excellent diastereoselectivity in good to excellent yields.
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