A new method for the synthesis of α-arylalkanoic acids by the use of 1, 2-rearrangement of the aryl group
G Tsuchihashi, K Kitajima, S Mitamura
Index: Tsuchihashi, Gen-ichi; Kitajima, Koji; Mitamura, Shuichi Tetrahedron Letters, 1981 , vol. 22, # 43 p. 4305 - 4308
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Citation Number: 31
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A simple synthetic method of α-arylalkanoic acids was accomplished by the use of a novel 1,2-rearrangement of the aryl group and this method was applied to the syntheses of some biologically important substances. ... As the reaction proceeds, p-toluenesulfonic acid is produced. ...
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[Gualtieri; Conti; Dei; Giovannoni; Nannucci; Romanelli; Scapecchi; Teodori; Fanfani; Ghelardini; Giotti; Bartolini Journal of Medicinal Chemistry, 1994 , vol. 37, # 11 p. 1704 - 1711]