Studies on Acetylenic Compounds. LVI. Syntheses of 4-Isoxazolin-3-ones and 1-Phenyl-3-hydroxypyrazoles

N NAKAMURA, Y KISHIDA, N ISHIDA

Index: Nakamura,N. et al. Chemical and Pharmaceutical Bulletin, 1971 , vol. 19, p. 1389 - 1394

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Citation Number: 12

Abstract

The reactions of α-acetylenic esters with N-substituted hydroxylamines in the presence of strong bases afforded 2-substituted 4-isoxazolin-3-ones, which were also prepared from α- acetylenic acid chlorides and N-substituted hydroxylamines. 1-Phenyl-3-hydroxypyrazoles were obtained by the reaction of α-acetylenic esters with phenylhydrazine in the presence of alkoxides.