Aryl-fused nitrogen heterocycles by a tandem reduction-Michael addition reaction
…, DM Herron, ML Ackerman
Index: Bunce, Richard A.; Herron, Derrick M.; Ackerman, Matthew L. Journal of Organic Chemistry, 2000 , vol. 65, # 9 p. 2847 - 2850
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Citation Number: 48
Abstract
The 1, 2, 3, 4-tetrahydroquinoline, 3, 4-dihydro-2H-1, 4-benzoxazine, and 1, 2, 3, 4- tetrahydroquinoxaline ring systems are important structural units in many bioactive compounds. 2-4 A review of the literature2-4 reveals that while the parent molecules are easily prepared, substituted cases are considerably more challenging. As part of our synthetic studies, we sought to prepare derivatives of these compounds by a tandem ...
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