Synlett

Conjugate Reduction of α, β-Unsaturated Aldehydes with Rhodium (bisoxazolinylphenyl) Catalysts

Y Kanazawa, H Nishiyama

Index: Kanazawa, Yoshinori; Nishiyama, Hisao Synlett, 2006 , # 19 p. 3343 - 3345

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Citation Number: 26

Abstract

The catalytic reduction of cinnamaldehyde (3) was carried out using Rh(t-Bu-Phebox)(OAc) 2 (aq) (1) [7] (1 mol%) and (EtO) 2 MeSiH (1.5 equivalents) in a toluene solution at 60 °C (Scheme [1] ). After desilylation, dihydrocinnamaldehyde (4) was obtained in 98% yield, no ...

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