Synthesis

Selective reduction of nitroarenes by a Hantzsch 1, 4-dihydropyridine: A facile and efficient approach to substituted quinolines

RG Xing, YN Li, Q Liu, YF Han, X Wei, J Li, B Zhou

Index: Xing, Rui-Guang; Li, Ya-Nan; Liu, Qiang; Han, Yi-Feng; Wei, Xia; Li, Jing; Zhou, Bo Synthesis, 2011 , # 13 p. 2066 - 2072

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Citation Number: 13

Abstract

Abstract An efficient reductive cyclization of o-nitrocinnamoyl compounds was achieved by employing a Hantzsch 1, 4-dihydropyridine ester as a biomimetic reducing agent in the presence of catalytic palladium on carbon. This approach was successfully applied to the synthesis of substituted quinolines.

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