A high-throughput screening assay for hydroxynitrile lyase activity
J Andexer, JK Guterl, M Pohl, T Eggert
Index: Andexer, Jennifer; Guterl, Jan-Karl; Pohl, Martina; Eggert, Thorsten Chemical Communications, 2006 , # 40 p. 4201 - 4203
Full Text: HTML
Citation Number: 30
Abstract
Hydroxynitrile lyases (HNLs) naturally occur in plants integrated in microbial and herbivore defense mechanisms by HCN-release due to cyanohydrin cleavage. Some HNLs are biochemically characterized in detail concerning substrate specificity and enantioselectivity. The HNLs from Prunus species, like P. amygdalus (bitter almond) 1a and P. mume (Japanese apricot) 1b as well as the HNL from Linum usitatissimum (flax) 1c show (R)-selectivity, whereas the other HNLs ...
Related Articles:
Catalytic oxidation of alcohols with polymer-supported ruthenium complex under mild conditions
[Kang, Qiao-Xiang; Luo, Ju-Jie; Bai, Yan-Bin; Yang, Zhi-Wang; Lei, Zi-Qiang Journal of Organometallic Chemistry, 2005 , vol. 690, # 26 p. 6309 - 6313]
Metal??Free Arylation of Oxygen Nucleophiles with Diaryliodonium Salts
[Jalalian, Nazli; Petersen, Tue B.; Olofsson, Berit Chemistry--A European Journal, 2012 , vol. 18, # 44 p. 14140 - 14149,10]
Design and synthesis of low molecular weight compounds with complement inhibition activity
[Master, Hoshang E.; Khan, Shabana I.; Poojari, Krishna A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 16 p. 4891 - 4899]
[Romanelli; Autino; Baronetti; Thomas Synthetic Communications, 2004 , vol. 34, # 21 p. 3909 - 3914]
[Nagayama; Shimizu; Yamamoto Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 10 p. 1803 - 1815]