First Highly Regio??and Diastereoselective [3+ 2] Cycloaddition of Chiral Nonracemic Fischer Carbene Complexes with Azomethine Ylides: An Enantioselective …

J Barluenga, MA Fernández??Rodríguez…

Index: Barluenga, Jose; Fernandez-Rodriguez, Manuel A.; Aguilar, Enrique; Fernandez-Mari, Felix; Salinas, Alejandro; Olano, Bernardo Chemistry - A European Journal, 2001 , vol. 7, # 16 p. 3533 - 3544

Full Text: HTML

Citation Number: 47

Abstract

Abstract A new procedure for the synthesis of 1, 3, 4-trisubstituted and 1, 4-disubstituted pyrrolidin-2-one derivatives in an enantioselective fashion is reported. The 1, 3-dipolar cycloaddition of (±)-menthol and (−)-8-phenylmenthol derived Fischer alkoxy alkenyl carbene complexes with in situ generated functionalized azomethine ylides gives the corresponding cycloadducts as chelated tetracarbonyl Fischer carbene complexes. Only ...

Related Articles:

Enantioselective Michael additions of nitromethane by a catalytic double activation method using chiral Lewis acid and achiral amine catalysts

[Itoh, Kennosuke; Kanemasa, Shuji Journal of the American Chemical Society, 2002 , vol. 124, # 45 p. 13394 - 13395]

Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1

[Wu, Baogen; Kuhen, Kelli; Ngoc Nguyen, Truc; Ellis, David; Anaclerio, Beth; He, Xiaohui; Yang, Kunyong; Karanewsky, Donald; Yin, Hong; Wolff, Karen; Bieza, Kimberly; Caldwell, Jeremy; He, Yun Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 13 p. 3430 - 3433]

Enantioselective Michael additions of nitromethane by a catalytic double activation method using chiral Lewis acid and achiral amine catalysts

[Itoh, Kennosuke; Kanemasa, Shuji Journal of the American Chemical Society, 2002 , vol. 124, # 45 p. 13394 - 13395]

Enantioselective Synthesis of 2, 3-Disubstituted Indanones via Pd-Catalyzed Intramolecular Asymmetric Allylic Alkylation of Ketones

[Yang, Xiao-Fei; Ding, Chang-Hua; Li, Xiao-Hui; Huang, Jian-Qiang; Hou, Xue-Long; Dai, Li-Xin; Wang, Pin-Jie Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 8980 - 8985,6 Title/Abstract Full Text Show Details Yang, Xiao-Fei; Ding, Chang-Hua; Li, Xiao-Hui; Huang, Jian-Qiang; Hou, Xue-Long; Dai, Li-Xin; Wang, Pin-Jie Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 8980 - 8985]

Co-catalyzed reductive cyclization of azido and cyano substituted α, β-unsaturated esters with NaBH 4: enantioselective synthesis of (R)-baclofen and (R)-rolipram

[Paraskar, Abhimanyu S.; Sudalai, Arumugam Tetrahedron, 2006 , vol. 62, # 20 p. 4907 - 4916]

More Articles...