Palladium-catalyzed R 2 (O) P directed C (sp 2)–H acetoxylation

H Zhang, RB Hu, XY Zhang, SX Li…

Index: Zhang, Heng; Hu, Rong-Bin; Zhang, Xiao-Yu; Li, Shi-Xia; Yang, Shang-Dong Chemical Communications, 2014 , vol. 50, # 36 p. 4686 - 4689

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Citation Number: 17

Abstract

A novel and efficient Pd-catalyzed C–H acetoxylation is described. The approach uses R 2 (O) P as a directing group to synthesize various substituted 2′-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields.

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