Novel and efficient catalytic route for the syntheses of tetrahydrofurans useful in the preparation of neonicotinoid insecticides

…, AR Ramulu, M Pardhasaradhi

Index: Potluri, Srinagesh Kumar; Ramulu, A. Raghu; Pardhasaradhi Synthetic Communications, 2005 , vol. 35, # 7 p. 971 - 978

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Abstract

Abstract Neonicotinoids are good alternatives to the widely used organophosphate insecticides (OP) and have gained enormous importance because of their low toxicity in vertebrates. An environmentally benign route for the synthesis of 3??(hydroxymethyl) tetrahydrofuran useful in the preparation of a neonicotinoid insecticide viz. MTI??446 is described. Principles of green chemistry such as hydroformylation, single??pot ...

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