Tetrahedron

Palladium-catalyzed carbonylative cyclization via trapping of acylpalladium derivatives with internal enolates. Its scope and factors affecting the C-to-O ratio

…, C Copéret, T Sugihara, I Shimoyama, Y Zhang, G Wu…

Index: Negishi, El-Ichi; Coperet, Christophe; Sugihara, Takumichi; Shimoyama, Izumi; Zhang, Yantao; Wu, Guangzhong; Tour, James M. Tetrahedron, 1991 , vol. 50, # 2 p. 425 - 436

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Citation Number: 43

Abstract

The Pd-catalyzed carbonylative cyclization reaction involving ω-acyl-substituted acylpalladium derivatives can proceed via intramolecular trapping with either C-or O- enolates; the preferential formation of either 5-or 6-membered rings dictates the C-to-O ratio in the trapping with enolates.

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