Stereoselective Ring Expansion of Vinyl Oxiranes: Mechanistic Insights and Natural Product Total Synthesis

…, LA Batory, JT Njardarson

Index: Brichacek, Matthew; Batory, Lindsay A.; Njardarson, Jon T. Angewandte Chemie - International Edition, 2010 , vol. 49, # 9 p. 1648 - 1651

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Citation Number: 23

Abstract

The central part of our research program is the development of broadly applicable atom- efficient synthetic methods to generate structural complexity. We recently reported a new copper-catalyzed ring expansion of vinyl oxiranes using commercially available, structurally simple, and air-stable copper (II) catalysts.[1] These studies demonstrated the success of this reaction for a broad range of substrates. Missing from these early studies were ...

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