Tetrahedron Letters

Catalytic homocoupling of aryl, alkenyl, and alkynyl halides with Ni (II)-complexes and zirconocene dichloride

J Peng, X Liu, Y Kishi

Index: Peng, Jianbiao; Liu, Xiang; Kishi, Yoshito Tetrahedron Letters, 2011 , vol. 52, # 17 p. 2172 - 2175

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Citation Number: 9

Abstract

We have been engaged in the development of catalytic Ni/Cr-mediated coupling reactions (Fig. 1). 1 and 2 With use of sulfonamide ligands, this coupling provides chiral allylic alcohols at the synthetically useful level. One of the by-products found in this process is the homodimer 4 of alkenyl iodide 2. Although it is formed only in an insignificant amount, 4 is uniformly found. Based on the Ni(0)-mediated homocoupling of aryl and alkenyl halides discovered ...

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