Catalytic C H Amination with Unactivated Amines through Copper (II) Amides
S Wiese, YM Badiei, RT Gephart, S Mossin…
Index: Wiese, Stefan; Badiei, Yosra M.; Gephart, Raymond T.; Mossin, Susanne; Varonka, Matthew S.; Melzer, Marie M.; Meyer, Karsten; Cundari, Thomas R.; Warren, Timothy H. Angewandte Chemie - International Edition, 2010 , vol. 49, # 47 p. 8850 - 8855
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Citation Number: 92
Abstract
Catalytic CÀH amination is an attractive strategy to prepare CÀN bonds without the need for a pre-functionalized site.[1–3] This approach offers substantial opportunities to streamline chemical syntheses by decreasing the number of functionalgroup manipulations such as “hydroxyl to amine”.[4] An appealing feature of this and related catalytic CÀH functionalization reactions is that protection steps may not be required for these ...
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